Chemistry of Organophosphorus Compounds

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Organophosphorus chemistry

Organophosphorus compounds are ubiquitous in nature, and due to their innate chemical properties, serve a fundamental role in a number of important fields. Among the more prominent features that elevate their status as a unique and versatile class of compounds, include variable oxidation states, multivalency, asymmetry and metal-binding properties. Their presence in bioactive natural products, ...

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Detection of organophosphorus compounds by covalently immobilized organophosphorus hydrolase.

As a consequence of organophosphorus (OP) toxins posing a threat to human life globally, organophosphorus hydrolase (OPH) has become the enzyme of choice to detoxify such compounds. Organophosphorus hydrolase was covalently immobilized onto a quartz substrate for utilization in paraoxon detection. The substrate was cleaned and modified prior to chemical attachment. Each modification step was mo...

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Esterases Reacting with Organophosphorus Compounds

The sixty-seven papers in this book are grouped under the following chapters: Esterase Structures, Catalytic Properties of Cholinesterases, Catalytic Properties of Paraoxonases and Related Esterases, Biology of Cholinesterases, Biology of Paraoxonases and Related Esterases, Toxicity and Degradation of Organophosphorus Compounds, Neuropathy Target Esterase, and Miscellaneous. The chapters are pr...

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Antioxidants in organophosphorus compounds poisoning.

Oxidative stress has recently been implicated as a factor in the mortality and morbidity induced by organophosphorus (OP) compound poisoning. An overwhelming number of research papers are based on studying at the cellular and organ level. Such studies have concluded that antioxidants can be used as an adjunct compound in the treatment of both chronic as well as acute OP poisoning. Still, the ro...

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Organophosphorus chemistry for the synthesis of dendrimers.

Dendrimers are multifunctional, hyperbranched and perfectly defined macromolecules, synthesized layer after layer in an iterative manner. Besides the nature of the terminal groups responsible for most of the properties, the nature of the internal structure, and more precisely of the branching points, is also of crucial importance. For more than 15 years, we have demonstrated that the presence o...

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ژورنال

عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan

سال: 1970

ISSN: 0037-9980,1883-6526

DOI: 10.5059/yukigoseikyokaishi.28.93